2014 MS of Pathogenic Microorganisms Complex Lipids

A.1.) Leishmania major sphingolipids and ethanolamine lipids ......................................... 3 A.1.a.) Sphingolipids are essential for differentiation but not growth in Leishmania .................... 3 A.1.b.) Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis. ................................................................................ 4 A.1.c.) Characterization of inositol phosphorylceramides from Leishmania major by tandem mass spectrometry with electrospray ionization. ....................................................... 5 A.1.d.) Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania. .................................................................................................. 5 A.1.e.) 55. Degradation of host sphingomyelin us essential for Leishmania virulence................... 6 A.1.f.) 72. Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence...................................................................................................... 8 A.1.g.) 70. Structural characterization of Leishmania infantum diradyl-glycerophosphoethanolamine lipids with cyclopropane fatty acid substituents by electrospray ionization multiple-stage linear ion-trap tandem mass spectrometry with high m/z resolution............................... 9 A.1.h.) 57. Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDPgalactose salvage pathway in Leishmania major....................................................... 11